Best Night Cream for Menopause · Oprah Daily

Calm

Deep Hydration Restorative Face Cream

Face · Eye · Neck · Specifically for Menopausal Skin

Your skin refuses to stay hydrated, shows more fine lines, and a loss of firmness and radiance.

Softer skin from day one. Firmer, smoother, more radiant skin in 8 weeks. Clinically proven.

  • Smooths · firms · brightens
  • Softens the look of fine lines · strengthens skin barrier
  • Clinical strength. Safe for reactive skin. Gentle enough for daily use.
  • 100% non-irritating · fragrance free
  • Revives menopausal skin
43 verified reviews · 5.0

Try Calm for 60 days. Full refund if you don't love it.

$132

60-90 day supply

  • 60-day money-back guarantee
  • Ships within 48 hours
  • Free shipping over $150
Apple Pay Google Pay American Express Mastercard PayPal Visa
Benefits

Calm is a clinical-grade cream engineered for the biology of menopausal skin. When used consistently, it can:

  • Rebuilds the barrier weakened by declining estrogenRestores the lipid layer estrogen loss depletes; holds hydration in, keeps irritants out.
  • Improves firmness and elasticitySupports the elastin networks and the dermal-epidermal structure intrinsic aging breaks down.
  • Softens the look of fine linesReduces the depth and pattern of fine lines around the eyes and mouth.
  • Calms reactive, sensitive skinReduces neurogenic inflammation and soothes the reactivity hormonal shifts can trigger.
  • Locks in deep, lasting hydrationPlumps, firms, and holds moisture with hydration that lasts all day.

Clinically proven at 8 weeks

94% improved radiance · 84% smoother skin · 81% more supple skin · 72% improved fine lines. Independent 8-week clinical trial · 32 women, aged 48 to 70.

Full Ingredients (INCI)

The 7 actives in Resilara-7™

  • Ceramide NP: rebuilds the lipid barrier depleted by declining estrogen levels.
  • FEMINAGE™ (Engelhardtia chrysolepis): targets menopausal skin by rebuilding elastin networks, blocking glycation damage, and restoring firmness, elasticity, and facial contour.
  • Lupine Peptides: strengthens the dermal-epidermal junction to improve firmness and elasticity.
  • Argireline® Amplified (Acetyl Hexapeptide-8): reduces expression lines by softening muscle contractions and accelerating skin recovery after each expression.
  • Algaktiv® RestoreSKN (Ruttnera Lamellosa Oil and Watanabea Reniformis Oil): restores the skin matrix by actively increasing collagen, elastin, and the skin's intrinsic growth factors.
  • EXPOZEN® (Hydrolyzed Rhodophycea): marine algae extract that calms reactive and sensitive skin by reducing neurogenic inflammation and rebalancing the skin microbiome.
  • White Truffle: rare white truffle extract that activates skin's repair genes to firm, plump, and deeply hydrate.

Water (Aqua), Cetearyl Alcohol, Propanediol, Caprylic/Capric Triglyceride, Coco-Caprylate, Simmondsia Chinensis (Jojoba) Esters, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Glyceryl Stearate, Ruttnera Lamellosa Oil, Watanabea Reniformis Oil, Hydrolyzed Lupine Protein, Engelhardtia Chrysolepis Leaf Extract, Hydrolyzed Rhodophycea (Red Algae) Extract, Tuber Magnatum (White Truffle) Extract, Acetyl Hexapeptide-8, Tocopherol, Linoleic Acid, Phytosterols, Phospholipids, Bisabolol, Zingiber Officinale (Ginger) Root Extract, Aloe Barbadensis Leaf (Aloe) Juice, Ceramide NP, Ectoin, Glyceryl Behenate/Eicosadioate, Helianthus Annuus (Sunflower) Seed Wax, Sodium Stearoyl Glutamate, Polyglycerin-3, Helianthus Annuus (Sunflower) Seed Oil, Helianthus Annuus (Sunflower) Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Cetyl Hydroxyethylcellulose, Xanthan Gum, Acacia Senegal Gum, Sodium Gluconate, Sodium Benzoate, Potassium Sorbate, Sodium Phytate, Lecithin, Caprylhydroxamic Acid, Caprylyl Glycol, Citric Acid.

Formulated without: Parabens · Phthalates · Sulfates · PEGs · SLSs · Fragrances · Essential oils · Known endocrine disruptors.

How to Use
  • AM & PM application.
  • Apply a pearl-sized amount to clean skin.
  • Upward sweeping motion · face, eye area, neck, décolletage.
  • Massage until thoroughly absorbed.
  • Add more as needed.

Susan's Tip

Whenever your skin needs extra comfort, use Calm as an overnight mask: apply an extra-thick layer and let it sink in before bed.

Clinical Evidence

8-week clinical efficacy trial

  • Independent 8 Week Clinical Trial · 32 subjects, aged 48–70.
  • Instrument ratings and expert clinical grading at baseline, week 4 and week 8.
  • Instrumentation: Corneometer (hydration), Tewameter (barrier), Cutometer (firmness/elasticity).
  • Week 8, statistically significant results: 94% improved radiance · 84% smoother skin · 81% more supple skin · 72% improved fine lines.
  • Photos verified unretouched.

Clinical irritation testing (100% non-irritating)

  • Independent clinical irritation study for primal dermal irritability, accumulated dermal irritability, and dermal sensitization.
  • 60 subjects · dermatologist-supervised · 6-week protocol.
  • Calm scored 0.00 indicating zero dermal irritability or sensitization.
  • Methodology: Human Repeat Insult Patch Test (HRIPT) under maximized conditions.
  • Validated for sensitive, reactive skin.

Other independent tests

  • Dermatologically tested: Board-certified dermatologist led safety assessment for cutaneous acceptability. 35 participants with zero adverse reactions.
  • Ophthalmologically Tested: Ophthalmologist led safety assessment for use around eye area. 35 participants with zero irritating or allergenic ocular reactions.
  • MyMicrobiome certified · Cruelty Free Leaping Bunny certified.

Is this for me?

Best for

  • Dryness, dullness, loss of firmness, fine lines, barrier weakness.
  • Hormonally-shifting skin: perimenopause, menopause, post-menopause.
  • All skin types, especially dry.
  • Also calms redness and sensitivity (secondary benefit).

Safe for

  • Sensitive skin (0.00 clinical irritation score).
  • Use around the eyes (ophthalmologist-tested).
  • Use with MHT.
  • Daily AM and PM use.

Not for

  • Anyone with a known allergy to any specific ingredient in the INCI list (check the Full Ingredients drawer).
Shipping & Returns
  • Free shipping on orders $150+.
  • Orders ship within 1–2 business days from Little Rock, AR.
  • Standard ground delivery: 3–10 business days within the continental US (Hawaii / Alaska: 5–14).
  • Expedited shipping available at checkout (rates calculated at cart).
  • 60-day money-back guarantee.
  • Returns: email support to start a return. Customer pays return shipping. Refund processed within 5–7 business days of warehouse receipt.
  • International shipping not currently available.

Your strongest skin for your strongest years.

Woman in midlife holding Phosis Calm

Is This Me?

A change in your skin.

  • Your hydration disappears by 2pm, no matter what you layer.
  • Products you trusted in your 30s are no longer working.
  • You look duller than you feel. Fine lines appear and skin begins to sag.
  • Your skin doesn't bounce back the way it used to.
  • Your skin looks tired; we know why because we've been there.

That's the gap Phosis was built to close.

Will This Help My Skin?

Why it works.

Powered by Resilara-7™. Our exclusive formula engineered for the biology of menopausal skin, not the symptoms.

Tested like a pharmaceutical.

The FDA requires zero clinical testing for cosmetic skincare. Calm was subjected to four independent clinical tests before it reached your skin.

  • Dermatologically tested: Board-certified dermatologist led safety assessment for cutaneous acceptability. 35 participants with zero adverse reactions.

  • Ophthalmologically Tested: Ophthalmologist led safety assessment for use around eye area. 35 participants with zero irritating or allergenic ocular reactions.

  • HRIPT clinical irritation study (60 subjects). Calm scored 0.00 indicating zero dermal irritability or sensitization.

  • 8-week clinical trial (32 subjects, aged 48-70). 94% improved radiance, 84% smoother skin, 81% more supple skin at Week 8 from instrument ratings and expert clinical grading.

Strong enough to deliver results. Gentle enough for sensitive, reactive skin.

Calm Deep Hydration Restorative Cream

How Long Until I See Results?

Results from Day 1.

  1. Day 1

    Deeply hydrates

    Skin feels softer and more supple after the first use.

  2. Day 14

    Soothing comfort

    A decrease in dryness and irritation as skin begins to regain moisture.

  3. Week 4

    Smoother, firmer

    Skin appears smoother and firmer with a decrease in elasticity.

  4. Week 8

    Vibrancy restored

    Radiance replenished: the look of fine lines are diminished for a more lifted and vibrant overall appearance

Timeline directional. Detailed clinical results below.

Can I Trust the Numbers?

Clinically proven to work on real women in midlife.

Smooths · Firms · Brightens · All clinically measured.

Week 8
Before

Clinical trial participant

Week 8
Before

Clinical trial participant

Week 8
Before

Clinical trial participant

94%
improved radiance
Week 8
84%
smoother skin
Week 8
81%
more supple skin
Week 8
72%
improved fine lines
Week 4
100%
non-irritating
0.00 Clinical Score

Independently verified. Four separate clinical trials: 8-week clinical trial · 32 women, aged 48-70 · Statistically significant measurements · Clinical Irritation Study · 60 subjects · 0.00 HRIPT irritation score · Dermatologically Tested · Opthalamologically Tested. Photos unretouched.

Verified Reviews

Real life results.

My skin used to be very dry especially around my eyes and mouth and this product has it feeling and looking moist and plumper! Amazing

Leslie Q. · Verified customer

I absolutely love this product. This felt gentle and nourishing, and my face looks so supple after using it. I was honestly surprised by how much I liked it because I am usually so cautious with anything I put on my skin.

Ashley D. · Verified customer

I have 61 year old menopause skin and eczema. After a little over a week using PHOSIS my face, neck, and chest are moisturized like they should be!! They feel good and all signs of eczema on my chest and my creases of my nose are gone.

Sandi L. · Verified customer

Why This, Not What I'm Using?

Most skincare wasn't built for this lifestage.

Your skin has changed, but your skincare hasn't. Phosis is designed to meet the menopausal shift instead of fight it.

Fragrance-free  ·  Endocrine-disruptor free  ·  100% non-irritating  ·  Independently verified

Phosis Legacy Anti-aging Skincare
Built for midlife / menopausal skin biology
Active ingredients at strengths that actually work Often trace amounts
Independently tested for sensitive skin 100% non-irritating Rarely tested
Independent clinical testing 4 tests 0 required by FDA
Fragrance-free · Known endocrine-disruptor free · MyMicrobiome™ certified · Yuka 100

Built by a woman who needed it.

Susan Campbell. Twenty-five years coaching women through midlife as a certified Pilates and yoga teacher, and 5 years as a certified menopause coach. When she entered perimenopause, the products she'd trusted for years started reacting against her changing skin. When she looked for a solution, she couldn't find clean, clinically proven skincare made for menopausal women.

So she trained as an organic skincare formulator and built it. Every formula is created from the ground up specifically for the biology of menopausal skin and then rigorously tested for safety and effectiveness.

“I create skincare for women who are tired of 'anti-aging' messaging and want clean formulas with proven results.”

xx, Susan  ·  Founder & CEO

Phosis in Motion

Real women. Real results.

The Synergy

Why they're better together.

Calm rebuilds. Luminous protects. Neither works alone the way both work together. Calm penetrates deeply to smooth, firm, brighten, reduce reactivity, and rebuild the skin barrier. Luminous absorbs quickly to seal in hydration, restore glow, and protect skin. Together, the Power Pair replaces a typical six-product menopause skincare routine. Safe for sensitive, reactive skin.

Calm
Luminous

Step 1 · Rebuild

Calm

After cleansing, apply a pearl-sized amount in upward sweeping motion to face, neck, and décolletage. Massage thoroughly until fully absorbed. Apply more as needed.

Step 2 · Protect

Luminous

One to two drops for face, neck, and décolletage. Apply over Calm to seal in moisture and reinforce skin barrier protection. Tip: add a drop to foundation for added daytime glow.
Calm Luminous

The Power Pair

Calm + Luminous · $218.00 (save $10)

Shop the Power Pair
Not sure if it's right for you?

Not sure if it's right for you?

Try the Discovery Set · 3-5 day supply of both · $30

Actives. 1 Powerful Complex. Meet Resilara-7™

Clean, pharmaceutical-grade ingredients, specifically matched to target the changes in menopausal skin.

The Phosis Complex

Resilara-7™

Our proprietary formula built for menopausal skin biology. Each active is selected and concentrated for a specific change menopause makes in your skin.

Not private-labeled. Not white-labeled. Not available anywhere else but Calm Deep Hydration Restorative Cream.

Algaktiv® RestoreSKN

Skin Matrix

Algaktiv® RestoreSKN

Restores the skin matrix by increasing collagen, elastin and the skin's own intrinsic growth factors. Helps the skin do its own repair work instead of just supplying the fix.

FEMINAGE™

Sagging defense

FEMINAGE™ Engelhardtia chrysolepis

Targets menopausal skin specifically. Rebuilds elastin networks, blocks glycation damage and restores firmness, elasticity and facial contour. Engineered for estrogen-deficient skin.

Lupine peptides

Collagen

Lupine peptides

Strengthens the dermal-epidermal junction, the seam where the top layers of skin attach to the deeper structural layers. That seam is where menopausal skin loses firmness first.

Argireline® Amplified

Expression lines

Argireline® Amplified

Reduces expression lines by softening the micro-muscle contractions that etch them. Accelerates skin recovery after every expression, further smoothing the skin.

+ 3 more actives: Ceramide NP, EXPOZEN® Hydrolyzed Rhodophycea, and White Truffle Extract.

See the full Resilara-7 science →

Radical Honesty

Who Calm isn't for.

A short list. Skincare that's for everyone is usually for no one.

  • Unexplained rashes. If you're experiencing new or unusual rashes on your skin, consult a dermatologist prior to starting a new skincare routine.
  • Simultaneous use with prescription tretinoin (Retin-A). Cycle tretinoin instead of daily use, or space by at least 30 minutes if your dermatologist approves.
  • Active acne as your primary concern. Calm is a barrier-and-firmness formula for the hormonal-shift face. If breakouts are your focus, we're not the right first stop.
  • Under 40 with no perimenopausal shifts yet. Your regular skin will do fine for now.

Give us 60 days to transform your skin. Love it or your money back.

Most women see a difference in the first week. If your skin doesn't look better after 8 weeks, we'll refund your purchase.